The results you’ll experience from your Anadrol cycles will vary significantly based on factors like your dose, your workout regimen, your diet, and any other supplements you take. These may include protein, creatine, or others. Remember that compounds like Anadrol work best when combined with healthy lifestyle changes that facilitate muscle growth, as well. Many bodybuilders have experienced gains upwards of 30 pounds in just six short weeks, but this is atypical. It’s far more likely you’ll experience gains of roughly 15 to 20 pounds.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are