Side effects of metenolone enanthate include symptoms of masculinization like acne , increased hair growth , voice changes , and increased sexual desire .  The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).   It has moderate anabolic effects and weak androgenic effects, as well as no estrogenic effects or risk of liver damage .   Metenolone enanthate is a metenolone ester and a long-lasting prodrug of metenolone in the body. 
Given the nature of many of the androgenic and estrogenic side effects from Trenbolone, it is often difficult to minimize the risk of negative effects while still preserving the efficacy of the drug. There are certainly methods that bodybuilders use to minimize the likelihood of harmful reactions, and the most important would be only taking anabolic-androgenic steroids under the supervision of a doctor who is well-versed in steroid use.
I think that if most bodybuilders objectively consider the long-term risks versus the short-term gains, it really won’t seem worth it in the end.