It should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health, including your cholesterol. Due to the ability of Letrozole- to inhibit estrogen so much, this should definitely be a concern to most users. However the research that has focused on the relationship between use of letrozole and cholesterol levels is rather inconsistent in it's findings. Many studies have concluded that the compound is detrimental to both a user's HDL and LDL cholesterol levels, while other research has found no link. Obviously individuals are best served to monitor their cholesterol while using any compound via blood tests however barring that, letrozole should simply not be run for extended periods of time if at all possible. Doing so could cause serious medical complications.
Along with the issues related to blood lipids is the fact that many users complain that their libido is dramatically reduced when using the compound. This is related to the fact that estrogen is partly responsible for the regulation of an individual's sex drive. Since Letrozole- is so potent it can often drive estrogen levels too low and this inhibits a user's libido. To avoid this users can lower dosages, but some anecdotally report that even extremely low doses of the drug can cause problems. If this is the case a less potent compound such as exemestane or anastrozole may be a more appropriate option.
Even with the use of liver protectants and aromatase inhibitors that may help reduce estrogenic or female type side effects, they are possible.
Anadrole Before & After Pictures Gained 25 LB lean muscle ★ ★ ★ ★ ★ Gaining 13lbs in 4 weeks and staying lean while still getting stronger was something I’ve not done before! Cole W. VIEW REVIEW Gained 9 LB muscle mass ★ ★ ★ ★ ★ I used to hammer curl 25 pounds I now can do it with 40’s. My before squat was 125 I now can hit 145. Allan Y. VIEW REVIEW Increased bench press by 20 LB ★ ★ ★ ★ ☆ My max bench was 205 before the cycle. After it moved up to 225. My body has shaped up so much more than before. Brandon C. VIEW REVIEW Gained 18 lb of muscle ★ ★ ★ ★ ★ I’ve gained over 18lbs of pure muscle, my biceps have gone from 15 inches to over 18 inches. Tony E. VIEW REVIEW
A user doesn’t have to have a predisposition to certain problems to experience negative side effects associated with any anabolic androgenic steroid. Other side effects are also possible.