Oxandrolone overdose

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Mirtazapine does not have serotonergic activity and does not cause serotonergic side effects or serotonin syndrome . [9] [61] This is in accordance with the fact that it is not a serotonin reuptake inhibitor or MAOI, nor a serotonin receptor agonist . [9] [61] There are no reports of serotonin syndrome in association with mirtazapine alone, and mirtazapine has not been found to cause serotonin syndrome in overdose. [9] [61] [105] However, there are a handful of case reports of serotonin syndrome occurring with mirtazapine in combination with serotonergic drugs like SSRIs, although such reports are unusual, very rare, and do not necessarily implicate mirtazapine as causative. [9] [106] [107] [108] [109] [110] The addition of mirtazapine to an MAOI does not cause serotonin syndrome, and has been considered to be a safe combination. [9] [61] Moreover, mirtazapine may actually be useful in the treatment of serotonin syndrome, with at least one publication finding it to be effective in resolving the syndrome. [9] [62] [111] This is in accordance with the fact that the 5-HT 2A receptor is the predominant serotonin receptor thought to be involved in the pathophysiology of serotonin syndrome (with the 5-HT 1A receptor seeming to be protective). [9] [61] Mirtazapine is a potent 5-HT 2A receptor antagonist, and cyproheptadine , a drug that shares this property, mediates recovery from serotonin syndrome and is well-established clinically as an antidote against it. [9] [112]

Oxandrolone overdose

oxandrolone overdose

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