When using oxymetholone, one should always consult a physician on a frequent basis and get your liver values checked. The effect on the blood pressure is drastic so its recommended that you use a anti-hypertensive drug in conjunction, especially if you already have a fairly high blood pressure. The use of Clomid or Nolvadex and HCG is advised as well towards the end of your oxymetholone use. Lastly, oxymetholone also has an ill effect on the glucose tolerance5, causing borderline diabetic situations. Something to be weary of if you yourself have been diagnosed with similar problems already.